Acute leukaemia immunophenotyping in bone-marrow routine sections
نویسندگان
چکیده
منابع مشابه
Immunophenotyping of acute lymphoblastic leukaemia in routinely processed bone marrow biopsy specimens.
AIMS To assess the value of immunophenotyping of acute lymphoblastic leukaemia (ALL) in routinely processed bone marrow trephine biopsy specimens and to establish a minimum panel of antibodies to assess lymphoid lineage and enable differentiation from acute myeloid leukaemia. METHODS 45 routinely processed bone marrow biopsy specimens (formalin fixed, paraffin embedded and mildly decalcified ...
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Background Classification of cancer subtypes by means of microarray signatures is becoming increasingly difficult to ignore as a potential to transform pathological diagnosis nonetheless, measurement of Indicator genes in routine practice appears to be arduous. In a preceding published study, we utilized real-time PCR measurement of Indicator genes in acute lymphoid leukaemia (ALL) and acute m...
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Eighty-four children with acute lymphoblastic leukaemia (ALL) who had relapsed in bone marrow were studied to assess whether treatment would be more successful if relapse was detected before the disease became clinically evident. Patients whose relapse was detected by routine bone marrow examination before the disease became apparent were compared with those whose relapse was suspected from cli...
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A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provid...
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Introduction: The incidence of Acute leukaemia both AML and ALL has been increasing over the years. Chemotherapeutic agents used in the treatment of acute leukemia cause damage to the hematopoietic environment of the bone marrow initially, followed by stages of hematopoietic recovery. The study of post chemotherapy bone marrow in acute leukemia is essential to analyse the response to chemothera...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1999
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.1999.01366.x